Document and Entity Information Document Type Document Annual Report Document Period End Date Document Transition Report Securities Act File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Shell Company ICFR Auditor Attestation Flag Entity Public Float Entity Common Stock, Shares Outstanding Entity Central Index Key Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag Auditor Firm ID Auditor Name Auditor Location Document Financial Statement Error Correction [Flag] CONSOLIDATED BALANCE SHEETS Statement [Table] Statement Statement [Line Items] Statement Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Total current assets Assets, Noncurrent [Abstract] Non-current assets: Property, Plant and Equipment, Net Property and equipment, net Property and equipment-net Operating Lease, Right-of-Use Asset Right-of-use assets Amount of cash and other long-term assets restricted as to withdrawal or usage, classified as noncurrent. Restricted Cash And Other Assets Noncurrent Other long-term assets Assets Total assets Liabilities and Equity [Abstract] Liabilities and Stockholders' Equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses and other current liabilities Accrued expenses and other current liabilities Deferred Income, Current Deferred grant income Operating Lease, Liability, Current Current portion of lease liabilities Long-Term Debt, Current Maturities Current portion of long-term debt Less: current portion of long-term debt Liabilities, Current Total current liabilities Liabilities, Noncurrent [Abstract] Long-term liabilities: Operating Lease, Liability, Noncurrent Long-term lease liabilities Long-Term Debt, Excluding Current Maturities Long-term debt, net of current portion Long-term debt, net Business Combination, Contingent Consideration, Liability, Noncurrent Long-term contingent consideration Liabilities, Noncurrent Total long-term liabilities Liabilities Total liabilities Commitments and Contingencies Commitments and Contingencies (Note 14) Equity, Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, $0.001 par value; 5,000,000 shares authorized as of December 31, 2025 and 2024 Common Stock, Value, Issued Common stock, $0.001 par value; 120,000,000 shares authorized as of December 31, 2025 and December 31, 2024; 27,849,725 and 6,091,182 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively Additional Paid in Capital Additional paid-in capital Retained Earnings (Accumulated Deficit) Accumulated deficit Equity, Attributable to Parent Balance as of end of period Balance as of beginning of period Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Class of Stock [Axis] Class of Stock [Domain] Represents information relating to non-redeemable, non-controlling series E preferred stock. Series E Non Redeemable Non Controlling Preferred Stock [Member] Series E Convertible Non-Redeemable Preferred Stock Represents information relating to non-redeemable, non-controlling series F preferred stock. Series F Non Redeemable Non Controlling Preferred Stock [Member] Series F Convertible Non-Redeemable Preferred Stock Series F Convertible Non-Redeemable Preferred Stock Represents information relating to non-redeemable, non-controlling series G preferred stock. Series G Non Redeemable Non Controlling Preferred Stock [Member] Series G Convertible Non-Redeemable Preferred Stock Represents information relating to non-redeemable, non-controlling series H preferred stock. Series H Non Redeemable Non Controlling Preferred Stock [Member] Series H Convertible Non-Redeemable Preferred Stock Represents information relating to non-redeemable, non-controlling series I preferred stock. Series I Non Redeemable Non Controlling Preferred Stock [Member] Series I Convertible Non-Redeemable Preferred Stock Represents information pertaining to series AA convertible non redeemable preferred stock. Series Aa Convertible Non Redeemable Preferred Stock [Member] Series AA preferred stock Series AA Convertible Non-Redeemable Preferred Stock Preferred Stock, Par or Stated Value Per Share Preferred stock, par value Preferred Stock, Shares Authorized Preferred stock, authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value Common Stock, Shares Authorized Common stock, authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Operating Expenses [Abstract] Costs and expenses: General and Administrative Expense General and administrative Research and Development Expense (Excluding Acquired in Process Cost) Research and development Amount of (gain) loss recognized on fair value adjustment of contingent consideration. (Gain) Loss on Fair Value Re-measurement of Contingent Consideration (Gain) loss on fair value remeasurement of contingent consideration (Gain) loss on fair value remeasurement of contingent consideration Operating Lease, Impairment Loss Impairment of right-of-use assets Operating Expenses Total costs and expenses Operating Income (Loss) Loss from operations Other Income and Expenses [Abstract] Other income (expense): Investment Income, Interest Interest income Interest Expense, Nonoperating Interest expense Interest expense Amount of grant income. Income From Grants Grant income Gain (Loss) on Extinguishment of Debt Gain on extinguishment of debt Gain on extinguishment of debt Other Nonoperating Income (Expense) Other income (expense), net Nonoperating Income (Expense) Total other income (expense) Net Income (Loss) Available to Common Stockholders, Basic Net loss Net loss Net loss attributable to common stockholders Earnings Per Share, Basic Net loss per share attributable to common stockholders-basic (in dollar per share) Net loss per share attributable to common stockholders, basic Earnings Per Share, Diluted Net loss per share attributable to common stockholders-diluted (in dollar per share) Net loss per share attributable to common stockholders, diluted Weighted Average Number of Shares Outstanding, Basic Weighted average shares outstanding-basic (in shares) Weighted Average Number of Shares Outstanding, Diluted Weighted average common shares outstanding -diluted (in shares) Statement of Comprehensive Income [Abstract] Statement of Comprehensive Loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Other comprehensive loss: Comprehensive Income (Loss), Net of Tax, Attributable to Parent Total comprehensive loss CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY Equity Components [Axis] Equity Component [Domain] Preferred Stock [Member] Preferred Stock Common Stock [Member] Common Stock Additional Paid-in Capital [Member] Additional Paid-in Capital Retained Earnings [Member] Accumulated Deficit Represents information pertaining to non-redeemable, non-controlling series AA preferred stock. Series Aa Non Redeemable Non Controlling Preferred Stock [Member] Series AA Convertible Non-Redeemable Preferred Stock Sale of Stock [Axis] Sale of Stock [Domain] Represents information pertaining to at the market offering. At The Market Offering [Member] At The Market Offering Represents information pertaining to Oxford settlement agreement. Oxford Settlement Agreements [Member] Oxford settlement agreement Represents information pertaining to Settlement agreement. Settlement Agreements [Member] Settlement agreement Increase (Decrease) in Stockholders' Equity [Roll Forward] Stockholders' Equity Shares, Outstanding Balance as of end of period (in shares) Balance as of beginning of period (in shares) Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering including an at-the-market offering. Stock Issued During Period Value New Issues At The Market At the market offering, net of offering costs Number of new stock issued during the period from the at-the-market offering. Stock Issued During Period Shares New Issues At The Market At the market offering, net of offering costs (in shares) Stock Issued During Period, Value, Stock Options Exercised Exercise of stock options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercised options (in shares) Exercise of stock options (in shares) Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures Issuance of common stock for vested restricted stock units Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Issuance of common stock for vested restricted stock units (in shares) Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock under employee stock purchase plan Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock under employee stock purchase plan (in shares) Stock Issued During Period, Value, Issued for Services Issuance of common stock to satisfy service contract Stock Issued During Period, Shares, Issued for Services Issuance of common stock to satisfy service contract (in shares) Value of stock issued pursuant to private placement during the period. Stock Issued During Period, Value, Private Placement Common stock offering, net of offering costs Number of shares of stock issued during the period pursuant to private placement. Stock Issued During Period, Shares, Private Placement Common stock offering, net of offering costs (in shares) Number of new stock issued during the period from the conversion of Series G Preferred Stock. Stock Issued During Period Shares New Issues Conversion Of Series G Preferred Stock Issuance of common stock upon conversion of Series G preferred stock Number of new stock shares issued during the period from the conversion of Series G Preferred Stock. Stock Issued During Period Shares New Issues Shares Conversion Of Series G Preferred Stock Issuance of common stock upon conversion of Series G preferred stock (in shares) Number of new stock issued during the period from the conversion of Series H Preferred Stock. Stock Issued During Period Shares New Issues Conversion Of Series H Preferred Stock Issuance of common stock upon conversion of Series H preferred stock Value of stock related to non-redeemable, non-controlling preferred stock issued during the period, net of stock value. Stock Issued During Period, Value, Non-redeemable Non-controlling Preferred Stock, Total Issuance of convertible non-redeemable non-controlling preferred stock, net of issuance cost Shares of new stock classified as non-redeemable, non-controlling Series E preferred stock. Issuance Of Non-redeemable Non-controlling Series E Preferred Stock, Shares Issuance of convertible non-redeemable non-controlling preferred stock, net of issuance cost (in shares) Stock Issued During Period, Value, Conversion of Convertible Securities, Net of Adjustments Issuance of common stock upon conversion of Preferred Stock Stock Issued During Period, Shares, Conversion of Convertible Securities Issuance of common stock upon conversion of Preferred Stock (in shares) Stock Issued During Period, Value, New Issues Aggregate market value Issuance of Common Stock, net of issuance cost Stock Issued During Period, Shares, New Issues Stock offering, net of issuance cost and underwriting fees (in shares) Issuance of Common Stock, net of issuance cost (in shares) APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation expense Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture Stock-based compensation expense (in shares) Represents information pertaining to the at-the-market (ATM) offering. At The Market [Member] ATM Payments of Stock Issuance Costs Payment of deferred offering costs Payment of offering cost The cash outflow for cost incurred directly with the issuance of temporary equity. Payments of Stock Issuance Costs, Temporary Equity Issuance of preferred stock-net of issuance costs Preferred stock issuance costs CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities: Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to cash used in operating activities: Depreciation, Depletion and Amortization Depreciation and amortization Amount of non-cash operating lease cost. Non Cash Operating Lease Non-cash operating lease cost Amortization of Debt Issuance Costs and Discounts Amortization of debt discount and other non-cash interest Share-Based Payment Arrangement, Noncash Expense Stock-based compensation Issuance of Stock and Warrants for Services or Claims Issuance of Common Stock for service rendered Fair value of share-based compensation granted to nonemployees as payment for settlement agreements. Issuance of Stock and Warrants for Settlement Agreements Issuance of Common Stock for Settlement Agreements Gain (Loss) on Disposition of Property Plant Equipment Loss on sale or disposal of property and equipment Other Noncash Income (Expense) Other non-cash losses Increase (Decrease) in Operating Capital [Abstract] Change in operating assets and liabilities: Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Increase (Decrease) in Other Noncurrent Assets Other long-term assets Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued expenses and other current liabilities The increase (decrease) during the reporting period in lease and noncurrent liabilities. Increase Decrease In Lease And Other Liabilities, Noncurrent Lease liabilities and other long-term liabilities Net Cash Provided by (Used in) Operating Activities Cash used in operations Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: The cash outflow associated with the acquisition of long-lived, physical and other assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. Payments To Acquire Property Plant And Equipment And Other Assets Purchases of property and equipment and other assets Net Cash Provided by (Used in) Investing Activities Net cash used in investing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: The amount of cash outflow of principal on venture debt facility. Payment of Principal on Venture Debt Facility Payment of principal and payment fee on debt The cash outflow for cost incurred directly with the issuance of common and preferred stock. Payments Of Common Stock And Preferred Issuance Costs Payment of issuance costs from issuance of common stock and Series I preferred stock Proceeds from Issuance of Convertible Preferred Stock Aggregate gross proceeds of convertible preferred stock Proceeds from issuance of Series AA preferred stock Proceeds from Issuance of Preferred Stock and Preference Stock Proceeds from issuance of Series G preferred stock, net of issuance costs of $62 Proceeds from issuance of common stock and Series H preferred stock, net of transaction costs. Proceeds from Issuance of Common Stock and Series H Preferred Stock Proceeds from issuance of common stock and Series H preferred stock, net of issuance costs of $218 Proceeds from Issuance of Common Stock Proceeds from common stock offerings, net of offering costs of $866 The cash inflow from the issuance of common stock and series I preferred stock. Proceeds From Issuance Of Common Stock And Series I Preferred Stock Proceeds from issuance of common stock and Series I preferred stock The amount of cash outflow for cash portion of dosing milestone. Payment O Cash Portion Of Dosing Milestone Contingent consideration related to Combangio acquisition Finance Lease, Principal Payments Payment of principal on finance lease Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised Proceeds from exercise of stock options and issuance of common stock under employee stock purchase plan Net Cash Provided by (Used in) Financing Activities Net cash (used in) provided by financing activities Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net (decrease) increase in cash and cash equivalents: Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Cash and cash equivalents at end of period Cash and cash equivalents at beginning of period Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Non-cash investing and financing activities: Stock Issued Issuance of common stock to satisfy service contract in additional paid-in capital Carrying value as of the balance sheet date of obligations incurred through that date and payable for issuance costs. Accrued Issuance Costs Issuance costs included in accrued expenses Supplemental Cash Flow Information [Abstract] Supplemental disclosure: Interest Paid, Excluding Capitalized Interest, Operating Activities Cash paid for interest Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Right-of-use assets obtained in exchange of finance lease obligations Nature of Business Business Description and Basis of Presentation [Text Block] Nature of Business